Chromium picolinate improves insulin sensitivity in obese subjects with polycystic ovary syndrome. Lydic ML, McNurlan M, Bembo S, Mitchell L, Komaroff E, Gelato M. Chromium picolinate reduces insulin resistance in polycystic ovary syndrome: Randomized controlled trial. The role of supplemental chromium remains controversial. Metformin versus chromium picolinate in clomiphene citrate-resistant patients with PCOs: A double-blind randomized clinical trial. Clinical Overview Use Chromium supplementation has been studied for a variety of indications, especially diabetes and weight loss, but clinical studies have shown inconsistent results. If you choose to supplement, please inform your healthcare professional.Īmooee S, Parsanezhad ME, Ravanbod Shirazi M, Alborzi S, Samsami A. However, one notable issue with chromium is poor absorption. Similarly, a study of five people with PCOS found that two months of supplementing chromium picolinate resulted in an improved glucose disposal rate, indicating improvement of insulin resistance (3).ĭespite this encouraging evidence, the studies of the impact of chromium picolinate on PCOS are still very small and we require a higher quality of evidence to be able to recommend chromium picolinate to people with PCOS. Because of these effects, chromium supplements are popularly used to help control blood sugar (glucose) & cholesterol levels, and promote weight loss. are intended only to complement health or supplement the diet. It had no impact on ovulation and pregnancy rate (1).Ī double-blind randomised control trial with 85 people with PCOS found that 6-months of supplementing with chromium picolinate reduced fasting serum insulin levels, increased the fasting glucose-insulin ratio, increased the chances of ovulation and regularity of menstruation (2). Chromium is an essential trace element and nutritional supplement that has garnered interest for use as a weight loss aid. Biogen Chromium Picolinate contributes to the maintenance of normal blood glucose levels. There is some evidence suggesting that chromium picolinate may impact insulin levels, blood sugar levels, ovulation and period regularity.Ī randomised control trial on 92 women found that chromium picolinate decreased fasting blood sugar and insulin levels over three months, similarly to metformin, but didn’t impact androgen levels. Results: At baseline, both the chromium and placebo groups had similar mean body mass index (BMI) (chromium 36 +/- 6.7 kg/m (2) versus placebo 36.1 +/- 7. When it comes to weight loss supplements, the use of chromium is often overlooked. If our insulin and blood sugar levels are not properly regulated, it could lead to a number of health issues, including symptoms of diabetes. Picolinate acid is an organic compound added in order to enhance gut absorption (1). Chromium is one of the minerals responsible for the regulation of insulin activity and blood sugar levels. Trivalent chromium is typically considered an essential trace mineral as we can’t make it in the body. Chromium picolinate is a supplement consisting of trivalent chromium and picolinate acid.
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